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M220 Focused-ultrasonicator

SKU: 500295

The M220 Focused-ultrasonicator™ offers the “Scientist’s Standard” in a compact, easy-to-use system making it the ideal DNA shearing solution for MiSeq™ and PGM™ users. AFA technology in the M220 eliminates operator-induced variations, improves recoveries, increases efficiency, and provides standardized results.

  • Proven gold standard used in genome centers worldwide
  • Real-time monitoring and integrated Quality Control with SonoLab software
  • Optimized pre-loaded mechanical DNA shearing protocols for fragment sizes of 150 to 5,000 bp


Key applications for the M220 include:

  • Mechanical Shearing for Next Generation Sequencing (NGS)
  • DNA/RNA Extraction from Formalin-Fixed, Paraffin-Embedded (FFPE) Tissue Samples, Dried Blood Spots (DBS), and Whole Blood for NGS
  • Chromatin Mechanical Shearing for ChIP-Seq
  • Biomarker Extraction for Research and Clinical Microbiology
  • Tissue disruption and homogenization
  • Cell lysis



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